The main challenge in bioprinting soft materials (with an elastic modulus below 100 kPa) is the deformation of the material during printing. For example, collagen, as one of the key components of the extracellular matrix, is highly important for bioprinting. However, printing collagen comes with significant limitations. **Omidafarinan Mohandesi Ayandeh** has addressed these limitations with its new product, **Support© bio-ink**. Support© enables 3D bioprinting of low-viscosity bio-materials (such as collagen, alginate, fibrin, dECM, gelatin methacrylate, hyaluronic acid, etc.) in complex geometries without the need for sacrificial inks or mechanical reinforcement using other materials (like gelatin methacrylate, cellulose alginate, etc.). Additionally, to support various cell types and specialized bio-inks, this product can be prepared in a wide range of buffers and cell culture media.
categories Bioinks, Cell-laden Bioinks
In this section, you can read the full description of the product, its features, and key benefits to become familiar with the product’s function and true value.
The main challenge in bioprinting soft materials (with an elastic modulus below 100 kPa) is the deformation of the material during printing. For example, collagen, as one of the key components of the extracellular matrix, is highly important for bioprinting. However, printing collagen comes with significant limitations. **Omidafarinan Mohandesi Ayandeh** has addressed these limitations with its new product, **Support© bio-ink**. Support© enables 3D bioprinting of low-viscosity bio-materials (such as collagen, alginate, fibrin, dECM, gelatin methacrylate, hyaluronic acid, etc.) in complex geometries without the need for sacrificial inks or mechanical reinforcement using other materials (like gelatin methacrylate, cellulose alginate, etc.). Additionally, to support various cell types and specialized bio-inks, this product can be prepared in a wide range of buffers and cell culture media.. .. .
technichal informations:
| title | Description |
|---|---|
| Name | Support© |
| Appearance | Powder |
| Packaging | Vial |
| Storage conditions | Room temperature |
| Shelf life | Six months |
| Sterility | Non-sterile |
| Application | Supports the printing of other low-viscosity bio-inks |
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Further suggestions
Low-temperature print bed module
This module enables control of the print bed temperature at a level lower than ambient temperature.
Automatic calibration module
The accuracy and speed of preparing the bioprinter are two key factors in the success of bioprinting, especially when printing complex geometries. When using multiple print modules, manual calibration of the device is a tedious task. The automatic calibration module performs all tasks related to device preparation, calibration, and adjustments automatically.
Electrospinning module
Electrospinning is one of the oldest and most widely used methods in tissue engineering, enabling researchers to produce nanofibers with very small diameters. However, limited precision in microfiber placement and inherent constraints in fabricating true three-dimensional tissues have led to reduced emphasis on this technique in modern tissue engineering. By using the Melt Electrowriting module, the advantages of electrospinning and bioprinting can be integrated within a single system. This approach compensates for the limitations of conventional electrospinning and enables the bioprinter to fabricate extremely fine and highly precise tissue structures. The use of Omid Afarinan’s high-temperature module alongside this module is recommended.
Imaging module
The imaging module enables capturing images of the printed structure during and after bioprinting. This module allows examination of the printed structure without removing it from the print environment, thereby increasing the speed and quality of structure printing. Unlike many European and American bioprinters, this module does not occupy the position of one of the print modules when installed, allowing the user to utilize all printer modules for material printing.
Coaxial printing module
By installing this module, coaxial printing from 2 to 4 cartridges mounted on the bioprinter becomes possible simultaneously.
Syringe printing module
This module is an ideal choice for printing low-viscosity materials. With precise pressure control, it reduces the shear stress applied to the bioink, thereby improving cell viability.
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Apatite©
The natural bone tissue structure consists of two components: mineral and organic. **Hydroxyapatite (HA)** with the chemical formula Ca10(PO4)6(OH)2 is the main component of the mineral part of bone, acting as a reinforcing phase within the organic bone matrix (collagen). Based on this, the research team at **Omidafarinan Mohandesi Ayandeh** has developed a specialized bio-ink called **Apatite©** for bone tissue engineering applications. A unique feature of this bio-ink is the uniform distribution of HA nanoparticles within the scaffolds produced via 3D bioprinting. Additionally, this product has been certified at the nanoscale by the National Nanotechnology Initiative.
Osteoink©
**Osteoink© bio-ink** is a composite made from the mineral components found in bone and teeth. Its excellent mechanical properties and tunable biodegradability make this bio-ink a suitable option for 3D bioprinting of hard tissues. The presence of mineral components in this composite also enhances its bioactivity and promotes bone growth within printed scaffolds. Osteoink© mimics the natural extracellular matrix of bone tissue, supporting cell proliferation and differentiation.
ColGel©
**ColGel© bio-ink** is a unique collagen-based bio-ink composed of type I collagen extracted from mouse tails and gelatin methacrylate, which forms crosslinks in the presence of photoinitiators such as Irgacure. Collagen, being the most abundant protein in the body, is a key component for cell culture and scaffold formation for various applications. Due to the optical and biochemical properties of ColGel©, this bio-ink can be used to create personalized implants for treating corneal diseases and for fabricating artificial lenses.
Alginate©
**Alginate© bio-ink** is a specialized bio-ink developed by **Omidafarinan**, based on the polymer alginate, providing an ideal environment for cell viability and bioprinting. Alginate© bio-ink crosslinks in the presence of calcium ions. To create a composition capable of ionic crosslinking, it can be combined with other bio-inks. For printing complex structures with Alginate© bio-ink, it is recommended to use **Support© bio-ink** from Omidafarinan.
AllGBone©
**AllGBone© bio-ink** is a unique commercial product from **Omidafarinan**, derived from the extracellular matrix (ECM) of human bone tissue combined with natural, biocompatible, and biodegradable polymers. This bone allograft exhibits high osteoinductive and osteoconductive properties and, due to its content of bone-specific proteins and growth factors, plays a crucial role in repairing damaged bone tissue by supporting cell proliferation, differentiation, and new tissue growth.
Mineral©
Bone tissue consists of two phases: mineral and organic. The mineral phase accounts for 60–70% of the total dry weight of bone. Calcium phosphate bioceramics are particularly important for bone repair due to their structural similarity to the mineral phase of bone. **Mineral© bio-ink** is a specialized product developed by **Omidafarinan Mohandesi Ayandeh**, designed with minerals similar to natural bone tissue to promote early-stage osteogenesis. Scaffolds printed with this bio-ink are 100% ceramic and gradually degrade during bone regeneration, eventually being replaced by new bone.. .
Support©
The main challenge in bioprinting soft materials (with an elastic modulus below 100 kPa) is the deformation of the material during printing. For example, collagen, as one of the key components of the extracellular matrix, is highly important for bioprinting. However, printing collagen comes with significant limitations. **Omidafarinan Mohandesi Ayandeh** has addressed these limitations with its new product, **Support© bio-ink**. Support© enables 3D bioprinting of low-viscosity bio-materials (such as collagen, alginate, fibrin, dECM, gelatin methacrylate, hyaluronic acid, etc.) in complex geometries without the need for sacrificial inks or mechanical reinforcement using other materials (like gelatin methacrylate, cellulose alginate, etc.). Additionally, to support various cell types and specialized bio-inks, this product can be prepared in a wide range of buffers and cell culture media.
