BioFab-X4

The fifth-generation bioprinter designed for high-throughput 3D cell culture and advanced biofabrication — shaping the next era of healthcare innovation.

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By combining multiple printing methods with four print nozzles, you can create more complex multi-material structures.

With four independent printheads, you can fabricate intricate constructs that better replicate natural tissue architecture and biological function.

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Open biomaterial compatibility

While we provide a rich library of biomaterials, the BIOFAB X SERIES is built to support a broad spectrum of third-party bioinks, giving researchers the freedom to experiment without limitations.

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Modular, Interchangeable print modules (heads)

Our advanced modular printing system enables quick interchangeability and high flexibility, making the BioFab X series an ideal choice for diverse biofabrication projects.

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Easy to use

The automatic calibration system, combined with the integrated display, provides an easy and intuitive user experience for this sophisticated device.

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Coaxial & Mixing Printing

Independent pressure control across multiple channels enables smooth and uninterrupted coaxial and composite printing.

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Multi-material printing

Featuring four modular printhead positions, the system offers unmatched ease for printing with multiple biomaterials.

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Temperature-controlled printbed

The printbed supports adjustable temperature settings from 4°C to 90°C, enabling precise handling of thermosensitive materials.

Expanding possibilities through enhanced capabilities

BioFab X has powered cutting-edge research worldwide — and now, with the BioFab-X4, we’re taking innovation to the next level.4we’re taking innovation to the next level.

FeaturesBioFab X1BioFab X2BioFab X4
Operation inside the laminar hood
UV Module
Interchangeable module capability
Number of printheads124
Independent pressure control
Coaxial & Mixing Printing
HEPA Filter
CE certification (European Conformity)

BioFab -X4

The fifth-generation of the 4-nozzle bioprinter from Omid Afrinan Company.
Experience printing 4 materials simultaneously

Possibility of using Clean Chamber technology for maximum cell protection or using a laminar hood

The proprietary Clean Chamber system, utilizing two powerful fans and a HEPA H14 filter, removes airborne particles and microorganisms, providing a sterile environment for printing. UV light and an interior design without sharp corners also contribute to this technology to enhance cellular safety and reduce contamination.
Before starting the experiment, activate the Clean Chamber function to ensure optimal conditions for cell health.

Open Material Platform – Bioprint Without Limits

Compatible with a wide range of biomaterials

While we provide a comprehensive selection of ready-to-use and tissue-targeted bioinks, we also recognize the critical role of custom material development. That’s why we designed the BioFab X4 —as part of the BioFab X series—with an open material platform to support compatibility with the broadest range of biomaterials. Whether you're formulating your own bioinks or utilizing our advanced development kits, the system is built to adapt to your research needs.

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Advanced Temperature Control for Maximum Material Compatibility

Print a broader variety of biomaterials and cell types with accurate temperature control of the printhead and printbed.

With precise temperature control in both the print head (4 – 250 °C) and the print bed (4 – 90 °C), you can easily work with temperature-sensitive materials such as collagen and gelatin. This flexibility in thermal regulation allows the use of a wider range of biomaterials and cell types, opening new horizons in bioprinting.

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Expand your research with a growing collection of versatile, interchangeable printheads

With an integrated system, you can access various biofabrication methods. This platform supports up to four print nozzles and multiple printing tools.
Utilize a single platform to access various biofabrication techniques, thanks to support for up to eight different printheads and toolheads. BioFab X is a leading 3D bioprinter equipped with a modular printhead system, allowing researchers to easily switch between printheads tailored to specific biofabrication tasks. As new options are added, your research capabilities continue to grow — enabling more flexibility and precision in your bioprinting projects.

Built for expanded possibilities

BioFab X offers advanced features that deliver unmatched flexibility, empowering you to achieve exceptional results across a wide range of applications—and far beyond.

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Spheroid & organoid generation

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3D models for drug discovery

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Organs-on-a-chip

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Food alternatives

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Biosensors

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Organ generation

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Bioassays

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Micropatterning

Technical specifications

Technical specificationsAmount
Outer Dimentions (H × W × L)880 × 420 × 550 (mm)
Weight50 kg (110 lb)
Maximum Build Volume120 × 90 × 90 (mm)
Build Surface CompatibilityMulti-well plates, petri dishes, glass slides
XY-axis theoretical resolution70 (µm)
Theoretical layer resolution10 (µm)
Pressure Range (internal pump)0-700 (KPa)
Pressure Range (internal pump)0-900 (KPa)
Printhead Slots
Photocuring Sources (built-in)۳۶۵، ۴۰۵، ۴۸۵، ۵۲۰ (nm)
Printbed Temperature Range4-90 °C (lowest temperature 17 °C below chamber temperature)
Printbed Temperature Range4-250 °C (printhead specific)
Filter Class, Chamber Air-flowHEPA 14
UV-SterilizationUV-C (275 nm)
Calibration OptionsManual and Automatic
User InterfaceIntegrated touchscreen display + Repetier and Simplify3D software
OS CompatibilityWindows
ConnectivityUSB – Type B (Ethernet)
Supported File Formats.gcode, .stl, .amf, .3mf, .obj
Power input100-240V, 50-60Hz
Fuse250 VAC, F6.3A

Start shaping the future of medicine today — try our bioprinter firsthand